There were 80 coaching changes in 2A Baseball. Here they are:
| Region 1 | School | New Coach | Previous Coach |
| Boys Ranch | Will Weiland | Lynn Weiland | |
| Claude | Trevor Cordova | Jeff Byrd | |
| Stinnett West Texas | Jeff Smith | Keith Hardin | |
| Turkey Valley | Greg Ramsey | Brett Tyler | |
| Abernathy | Shane Karnbach | Jon Horne | |
| Floydada | Scotty Bruington | Brady Webb | |
| Ralls | Chance Rodriguez | Lynn Turner | |
| Morton | Travis Buchanan | Jimmy Randolph | |
| O’Donnell | Blandon Hancock | Blandon Hancock | |
| Sundown | Kevin Torres | Cory Barnes | |
| Fort Hancock | Mando Aguilar | Armando Aguilar | |
| McCamey | Santos Saucedo | Chris Arredondo | |
| Roby | Ryan Cronkright | Nick Dickson | |
| Rotan | Kyle Giusti | Brad Baker | |
| Cross Plains | Mark Kelley | Daniel Kelley | |
| San Saba | Jeff Pannell | Cory Moreno | |
| Anson | Scotty Nichols | Cash Fortune | |
| Baird | Joe Martinez | Chance Rodriguez | |
| Clyde Eula | Josh Fosel | Donald Beard | |
| Hamlin | Ryne Lucas | Chris Simmons | |
| Region 2 | School | New Coach | Previous Coach |
| Archer City | Don Hasley | Wes Johnson | |
| Poolville | Doug McCollough | Doug McCollough | |
| Bells | Logan Turner | Lance Johnson | |
| Blue Ridge | Pete Vamvakas | John Ramsey | |
| Celeste | Louis Park | Boe Parr | |
| Wolfe City | Kirk Ashby | Billy Eldridge | |
| De Leon | Reggie Patrick | Blake Rives | |
| Gordon | Jerry Tomlin | Jerry Tomlin | |
| Lipan | Brent Gaylor | ||
| Ranger | Shane Tuck | Trey Felan | |
| Hamilton | Cameron Bankston | Stephen Smith | |
| Covington | Kevin Scheler | Wayne Ware | |
| Frost | Chase Adams | Coy Barker | |
| Italy | Dan Weaver | Jon Cady | |
| Waxahachie Faith Family | Chris Murray | Parker Sheets | |
| Region 3 | School | New Coach | Previous Coach |
| Bogota Rivercrest | Rick Connot | Andy Spear | |
| Simms Bowie | Drew Webster | Charles Downs | |
| Cumby | Jason Keeney | Sonny Birdwell | |
| Cumby Miller Grove | Gary Billingsly | Gary Billingsly | |
| Saltillo | John Carlisle | Dalton Herndon | |
| Big Sandy | Chuck Isaac | Jeff Blackstone | |
| Gilmer Union Hill | Caleb Hensley | Clifton Arakaki | |
| Ore City | Craig Blakenship | Keith Touchstone | |
| Cayuga | Tony Humphreys | Michael Blackmon | |
| Malakoff Cross Roads | Evan Harrison | Chris Curran | |
| Martins Mill | Blaine Spradley | Kory Toney | |
| Trinidad | Scott Hayes | Travis Rhoten | |
| Latexo | Dillon McDugle | Bucky Nance | |
| Normangee | Justin Dunnam | Chris Nolen | |
| North Zulch | Matt McManemin | Josh McClendon | |
| Apple Springs | Cody Moree | Jacob McMurtry | |
| Kennard | Leo Denman | Leo Denman | |
| Wells | Tony Watkins | Tony Watkins | |
| Mount Enterprise | Evan Delafield | Josh Bragdon | |
| Brookeland | Mike Hallam | Casey McBryde | |
| Chester | Ed Brake | Chris Moore | |
| Colmesneil | Ross McMurry | Jacob Hooker | |
| San Augustine | James Ward | Seth Hubbard | |
| Zavalla | Chase Greening | Jerry Cobb | |
| Region 4 | School | New Coach | Previous Coach |
| Dallardsville Big Sandy | Jacob Hooker | Shane Nutt | |
| High Island | John Bronkhorst | Trad Taylor | |
| Sabine Pass | Elmer Laird | Troy Gragg | |
| Saratoga West Hardin | Michael Atkinson | Landon Hessler | |
| Dime Box | Daniel Bolton | ||
| Buckholts | Emilo Granado | William France | |
| Thrall | Brandon Lillard | Matthew Barnett | |
| Ganado | Kristopher Cavazos | Rick Ragsdale | |
| Louise | Manny Freeland | Joe Bill | |
| Schulenburg | Victor Camarillo | Robert Barber | |
| Johnson City | Stephen Wisdom | Casey Buaas | |
| Falls City | Danny Gonzalez | Damian Van Winkle | |
| Knippa | Josh King | No Program | |
| San Antonio Hawkins | Trey Doebbler | Rich Richmond | |
| Nordheim | Kevin Wilson | No Program | |
| Runge | Lucio Velasquez | Jim Rowe | |
| Agua Dulce | Matthew Gonzalez | John Rodriguez | |
| Ben Bolt-Palito Blanco | Will Foster | Frank Galvin | |
| Bruni | Mark Morales | Mark Morales | |
| Lasara | David Contreras | Oziel Ochoa | |
| San Perlita | Marco Mungia | Rey Garza |
