| Pick | Round | Player | Position | High School | MLB Team | |
| 17 | 1 | Forrest Whitley | P | SA Alamo Heights | Houston Astros | |
| 24 | 1 | Hudson Sanchez | SS | Southlake Carroll | SAn Diego Padres | |
| 44 | 2 | Kyle Muller | P | Dallas Jesuit | Atlanta Braves | |
| 85 | 3 | Mason Thompson | P | Round Rock | San Diego Padres | |
| 101 | 3 | Dustin May | P | Northwest | Los Angeles Dodgers | |
| 152 | 5 | Conner Capel | OF | Katy Seven Lakes | Cleveland Indians | |
| 182 | 6 | Ulysses Cantu | 3B | FW Boswell | Cleveland Indians | |
| 513 | 17 | Kidany Salva | C | Klein Forest | Minnesota Twins | |
| 549 | 18 | Marcus Mack | P | Bellaire | Texas Rangers | |
| 574 | 19 | Jarrett Gonzales | C | SA Madison | Washington Generals | |
| 578 | 19 | Evan Alexander | OF | Hebron | New York Yankees | |
| 630 | 21 | John McMillon | P | Jasper | Tampa Bay Rays | |
| 660 | 22 | Freddy Villareal | P | Brownsville Veterans | Tampa Bay Rays | |
| 668 | 22 | Blair Henley | P | Arlington Heights | New York Yankees | |
| 679 | 23 | Griffin Benson | 1B | Aledo | Atlanta Braves | |
| 776 | 26 | Zach Farrar | CF | Southlake Carroll | Chicago White Sox | |
| 964 | 32 | Garrett Gonzales | 3B | SA Madison | Washington Generals | |
| 990 | 33 | Hayden Wesneski | P | Cy Fair | Tampa Bay Rays | |
| 1032 | 34 | Shea Langeliers | C | Keller | Toronto Blue Jays | |
| 1045 | 35 | Jacob White | C | Frisco Wakeland | Detroit Tigers | |
| 1054 | 35 | Tristan Bayless | P | Hutto | Washington Generals | |
| 1057 | 35 | Nick Slaughter | C | Klein | Houston Astros | |
| 1163 | 39 | Caleb Scires | LF | Fairfield | Miami Marlins | |
| 1187 | 40 | Trey Morris | P | Katy Taylor | Philadelphia Phillies | |
| 1199 | 40 | Jordan Wiley | CF | Richland | Arizona Diamondbacks | |
| 1210 | 40 | Michael Chambers | C | Plano John Paul II | New York Mets |
*
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